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Therapeutic effects of simultaneous intraluminal irradiation and intraluminal hyperthermia on oesophageal carcinoma

N Fuwa, MD1, Y Nomoto, MD2, K Shouji, MD2, T Kodaira, MD1, M Kamata, MD1 and Y Ito, MD1

1Department of Radiation Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusaku, Nagoya 464-0021 and 2Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu 514-8507, Japan



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  		Figure 1. The applicator tip for delivering intraluminal hyperthermia. Top: A 6 F radiation source is inserted into the centre of the applicator, which has a 10 mm diameter balloon. Bottom: An endoscope, 2.2 mm in diameter, is inserted into the centre of the applicator, which has a 15 mm diameter balloon.

 


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  		Figure 2. The temperature distribution by thermography in an agar phantom. The temperature of thecooling water was 40 °C and the output was computer-controlled to achieve an applicator surface temperatureof 42–43 °C. Heating time was 15 min. The temperature of point x was 45.1 °C.

 


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  		Figure 3. The temperature distribution by thermography in an agar phantom. The temperature of thecooling water was 20 °C and the output was computer-controlled to achieve an applicator surface temperature of 42–43 °C. Heating time was 15 min. The temperature of point x was 51.9 °C.

 


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  		Figure 4. A dummy source tube was inserted into thecentre of the applicator in Case 1. After 40 Gy external beam irradiation, simultaneous intraluminal irradiation and intraluminal hyperthermia was administered once weekly for 3 weeks.

 


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  		Figure 5. A composite figure of the dose distribution during intraluminal irradiation and the heat distribution in Case 1.

 




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