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Value of protein-bound radioactive iodine measurements in the management of differentiated thyroid cancer treated with 131I

P A G Hammersley, PhD 1 A Al-Saadi, MD, PhD 1 S Chittenden, BSc 2 G D Flux, PhD 2 V R McCready, DSc, FRCP, FRCR 2 and C L Harmer, FRCP, FRCR 3

1 Departments of Nuclear Medicine 2 Physics 3 Clinical Oncology Thyroid Unit, Royal Marsden Hospital NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK



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Figure 1. 6-day protein-bound iodine-131 (PBI131) and scan at 3 days. The horizontal bars represent the mean value of the PBI131 for each group.

 


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Figure 2. Estimated absorbed radiation dose to the thyroid and the area under the curve (AUC) for protein-bound iodine-131 against time from 1–6 days corrected for administered dose.

 


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Figure 3. Area under the curve (AUC) of protein-bound iodine-131 (PBI131) % dose l-1 with time from 1–6 days against PBI131 % dose l-1 at 6 days.

 


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Figure 4. Estimated absorbed radiation dose to the thyroid against 6-day protein-bound iodine-131 (PBI131) % dose l-1.

 





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