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Non-specific interstitial pneumonia showing a "crazy paving" pattern on high resolution CT

E Coche, MD 1 B Weynand, MD 2 P Noirhomme, MD 3 and T Pieters, MD 4

1 Departments of Radiology 2 Pathology 3 Surgery 4 Pneumology, Cliniques Universitaires St-Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium



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  		Figure 1. Posteroanterior chest radiograph at time of onset of symptoms shows patchy consolidation in the right lower lobe.

 


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  		Figure 2. (a) High resolution CT (lung windows), 15 days after Figure 1Go, show geographic areas of ground-glass opacification associated with smoothly thickened interlobular septa (arrows) in both lower lobes. This appearance is called the "crazy paving" pattern. (b) The same abnormalities were present in the right middle lobe (arrow).

 


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  		Figure 3. Lung biopsy: the pulmonary parenchyma is homogeneously affected. Interalveolar septa are thickened by an inflammatory infiltrate and only slight fibrosis (haematoxylin and eosin, magnificationx43).

 




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