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Improving the sensitivity of stereotactic core biopsy to diagnose ductal carcinoma in situ of the breast: a mathematical model

N J Coombs, FRCS1, J R L Laddie, BM1, G T Royle, FRCS1, C M Rubin, FRCR2 and M S Briley, FRCR3

1 Departments of Breast Surgery
3 Radiology, Royal South Hants Hospital, Southampton
2 Southampton and Salisbury Breast Screening Unit, Southampton, UK



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  		Figure 1. Theoretical probability of retrieving at least one diagnostic core of ductal carcinoma in situ (DCIS) from 10 mm diameter focus of DCIS and 7.5% DCIS duct density.

 


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  		Figure 2. Theoretical probability of retrieving at least one diagnostic core of ductal carcinoma in situ (DCIS) from DCIS foci of varying diameter, with increasing number of core samples removed and 7.5% DCIS duct density. {square}, 1 core; {lozenge}, 3 cores; {triangleup}, 5 cores; X, 7 cores.

 




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