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A purpose-built iodine-125 irradiation plaque for low dose rate low energy irradiation of cell lines in vitro

E G Aird, PhD, FIPEM 1 M Folkard, BSc, PhD 2 C R Mayes, BSc 2 P J Bownes, BSc, MSc 1 J M Lawson, BSc, MSc 1 and M C Joiner, MA, PhD 2

1 Medical Physics Department, Mount Vernon Hospital, Northwood, Middlesex, HA6 2RN 2 Gray Laboratory Cancer Research Trust, PO Box 100, Mount Vernon Hospital, Northwood, Middlesex, HA6 2JR, UK



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  		Figure 1. (a) Complete assembly showing cell dish on top of plaque inside protected container. The cells to be irradiated form a layer on the surface of the dish at a fixed distance from the plaque; the liquid level indicated in the drawing is that of fluid used to keep the cells sustained during irradiation. (b) Arrangement of nine seeds on the plaque.

 


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  		Figure 2. Isodose distribution showing percentage levels with respect to mean dose rate used for the first plaque (scale in cm).

 




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