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Coronary myocardial bridging in Noonan syndrome: definitive diagnosis with high-resolution CT

Departments of ¹ Pediatric Cardiology and ² Pediatric Radiology, University Paris Descartes, Hôpital Necker-Enfants Malades, AP-HP, Paris, France

Correspondence: Doctor Phalla Ou, Department of Pediatric Radiology, Hôpital Necker-Enfants Malades, 149, rue de Sèvres 75743 Paris Cedex 15, France. E-mail: phalla.ou{at}nck.ap-hop-paris.fr

Noonan syndrome is an autosomal dominant disorder reported at an incidence of 1 in 1000–2500 live-born patients. Pulmonary stenosis with a dysplastic pulmonary valve and hypertrophic cardiomyopathy are often associated with this syndrome. We report on a 9-year-old patient affected by Noonan syndrome with left ventricle hypertrophy, in whom a sudden clinical presentation of chest pain after effort led to the clinical suspicion of associated coronary myocardial bridging, which was confirmed by high-resolution CT. We also review the literature on this topic.