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British Journal of Radiology (2008) 81, e228-e230
© 2008 British Institute of Radiology
doi: 10.1259/bjr/22456532
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British Journal of Radiology 81 (2008),e228-e230 ©2008 The British Institute of Radiology

Case report

Localized mediastinal lymph node amyloidosis showing an unusual unsynchronized pattern of enlargement and calcification on serial CT

H MATSUGUMA, MD 1 H SUZUKI, MD 1 Y ISHIKAWA, MD 1 R NAKAHARA, MD 1 T IZUMI, MD 2 S IGARASHI, MD 3 and N MIYAZAWA, MD 1

Departments of 1 Thoracic Surgery, 2 Hematology and 3 Pathology, Tochigi Cancer Center, Utsunomiya, Tochigi, Japan

Correspondence: Haruhisa Matsuguma, Division of Thoracic Surgery, 4-9-13 Yohnan, Utsunomiya, Tochigi 320-0834, Japan. E-mail: hmatsugu{at}tcc.pref.tochigi.jp

Amyloidosis is an unusual cause of mediastinal lymphadenopathy. A localized form of amyloidosis manifesting solely in the intrathoracic lymphnode is extremely rare. We describe a case of intrathoracic lymphadenopathy caused by a localized form of amyloidosis. Calcification has been reported in amyloidosis; however, it has been considered as non-specific. In our case, serial CT carried out over a period of 3 years and 3 months showed an unusual and unsynchronized pattern of enlargement and calcification.






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