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Massive cryptococcal lymphadenopathy in an immunocompetent pregnant patient

Departments of ¹ Radiology and ² Pulmonology and Critical Care, Department of Medicine, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

Correspondence: Dr Fathima Vawda, Principal Radiologist/Lecturer, Department of Radiology, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, Private Bag 7, Congella, Durban 4013, South Africa. E-mail: vawdaf{at}webmail.co.za; vawdaf1{at}ukzn.ac.za

Isolated pulmonary cryptococcosis remains a rare entity among pregnant or parturient patients who are immunocompetent, with few documented cases in the literature. We report a case of massive mediastinal lymphadenopathy in an immunocompetent pregnant patient with isolated pulmonary cryptococcosis. The unusual radiographic presentation of the present case merits special emphasis. Cryptococcal lymphadenopathy has a low prevalence in immunocompetent hosts and is more usually associated with an immunocompromised status. The occurrence of massive cryptococcal lymphadenopathy in an immunocompetent host is rare with previously reported cases occurring in non-pregnant patients.