BJR
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
First published online September 17, 2007
British Journal of Radiology (2007) 80, 782-789
© 2007 British Institute of Radiology
doi: 10.1259/bjr/99366083
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lai, C
Right arrow Articles by Han, G C
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lai, C
Right arrow Articles by Han, G C

Full paper

White matter tractography by diffusion tensor imaging plays an important role in prognosis estimation of acute lacunar infarctions

C Lai, MD 1 S Z Zhang, MD, PhD 2 H M Liu, BSc 3 Y B Zhou, BSc 1 Y Y Zhang, MSc 1 Q W Zhang, PhD 2 and G C Han, BSc 2

1 Department of Radiology, The Children's Hospital, 2 Department of Radiology, The Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 3 Department of Radiology, The Longsai Hospital, Ningbo, Zhejiang, China

Correspondence: Dr Can Lai, Department of Radiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003 China. E-mail: laican1{at}126.com

The aim of this study was to evaluate the anatomical and clinical relationship between lacunar infarction and the corticospinal tract (CST) in patients with acute lacunar infarction and predict clinical outcome. We examined 28 pyramidal tract stroke patients in the acute phase or early subacute phase (<3 days) with a marked motor deficit. The anatomical location and the extent of CST involvement within the infarcts were visualized on three-dimensional colour-coded diffusion tensor tractography (DTT). With regard to the CST, all patients were divided into three clinical subgroups: Group 1 (intact type), Group 2 (partial involvement type) and Group 3 (whole involvement type). Subsequently, the severity of the motor deficit of each patient was determined according to the National Institutes of Health Stroke Scale (NIHSS) scores at the acute/early subacute phase (<3 days after onset of symptoms), early chronic phase (8–14 days) and outcome (30–60 days). NIHSS scores of Group 1 (12/28) were significantly lower than those of Group 2 (9/28) at the acute phase or early subacute phase (U = –2.816, p<0.01), and those of Group 2 were significantly lower than those of Group 3 (7/28) (U = –3.136, p<0.01). At outcome,NIHSS scores of Group 1 were significantly lower than those of Group 2 (U = –2.846, p<0.01), and scores of Group 2 were significantly lower than those of Group 3 (U = –3.130, p<0.01). At the same time, the NIHSS scores of each group gradually decreased from acute phase to outcome, Neurological improvement was statistically different among the three topographical types of infarction (H = 26.15, p<0.01; H = 11.03, p<0.01; H = 10.05, p<0.01). In conclusion, the three-dimensional colour-coded DTT allows in vivo differentiation of distinct CST stroke subtypes and may help in better establishing the prognosis for patients after CST stroke.




This article has been cited by other articles:


Home page
 StrokeHome page
The STEPS Participants
Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): Bridging Basic and Clinical Science for Cellular and Neurogenic Factor Therapy in Treating Stroke
Stroke, February 1, 2009; 40(2): 510 - 515.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Radiol.Home page
BJR review of the year -- 2007
Br. J. Radiol., April 1, 2008; 81(964): 265 - 269.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
BJR DMFR IMAGING  ALL BIR JOURNALS 
Copyright © 2007 by the British Institute of Radiology.