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Imaging of Wegener's granulomatosis

Department of Imaging, Imaging Sciences Department, Hammersmith Hospital, Imperial College Faculty of Medicine, Du Cane Road, London W12 ONN, UK

Correspondence: Steven Allen, Department of Imaging, Royal Marsden Hospital, Fulham Road, London SW3 6JJ. E-mail: stevendallen{at}hotmail.co.uk

Wegener's granulomatosis is an uncommon multisystemic disorder of unknown aetiology. It is characterized histopathologically by necrotizing granulomatous vasculitis. Most commonly this involves the upper and lower respiratory tract, with pulmonary involvement occurring at some stage of the disease in almost all patients. However, many other organ systems can also be affected including the kidneys, orbits and central nervous system. For this pictorial review, we have assessed the imaging of 155 patients over a 10-year period in order to illustrate characteristic and some of the more unusual imaging features of Wegener's granulomatosis.

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