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First published online May 25, 2006
British Journal of Radiology (2007) 80, 132-139
© 2007 British Institute of Radiology
doi: 10.1259/bjr/20286459
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Pictorial review

Pearls and pitfalls of radionuclide imaging of the lymphatic system. Part 1: sentinel node lymphoscintigraphy in malignant melanoma

A F Scarsbrook, BMBS, BMedSci, FRCR, A Ganeshan, MRCP and K M Bradley, MRCP, FRCR

Department of Radiology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK

Correspondence: Dr Kevin Bradley, Consultant Radiologist & Nuclear Medicine Physician, Department of Radiology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK

Radionuclide imaging of the lymphatic system has a major role in the management of two main patient groups. First, pre-operative lymphoscintigraphy is a highly accurate method of sentinel node localization and can help guide minimally invasive surgery in a variety of tumour groups. Second, lymphoscintigraphy can play a pivotal role in assessing the cause of extremity swelling. This is the first of two pictorial essays on radionuclide imaging of the lymphatic system and will focus on sentinel node imaging in malignant melanoma. Regional nodal sampling is routinely performed in an increasing number of tumour groups and is well established in malignant melanoma and breast carcinoma. Careful attention to technical performance and image interpretation is essential to maximize the clinical utility of the test. This article provides a pictorial review of the interpretative pearls and pitfalls of sentinel node lymphoscintigraphy in malignant melanoma patients.




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