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Department of 1Nuclear Medicine and Tracer Kinetics 2Otolaryngology and Sensory Organ Surgery 3Pathology 4Radiology 5Clinical Oncology and Surgery and 6Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
Correspondence: Keisuke Enomoto, Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita City, Osaka, 565-0871, Japan. E-mail: keisuke.enomoto{at}tracer.med.osaka-u.ac.jp
Castleman's disease (CD) appears at ubiquitous lymph nodes. To date, detection of the lesion focus for CD has mainly been carried out by physical examination and radiological findings, such as X-ray analysis, CT and MRI. 18F-FDG PET visualizes the active focus of glucose metabolism and the clinical value has been investigated for many different tumours. Previous studies of 18F-FDG PET for CD have only reported four cases of unicentric CD and no cases of multicentric CD. In this paper, we report two cases of CD, one with unicentric CD and one with multicentric CD. We demonstrate that the use of 18F-FDG PET for the detection and monitoring of patients with CD, especially multicentric CD, would be effective.
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