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Disseminated mucormycosis in haematological patients: CT and MRI findings with pathological correlation

Departments of ¹Diagnostic Radiology ²Internal Medicine II ³Pathology ⁴Radiology ⁵Neuropathology, Eberhard-Karls-University, Hoppe-Seyler-Str.3, 72076 Tübingen, Germany

Disseminated mucormycosis is a rare, mostly fatal infectious complication in immunocompromised haematological patients. The purpose of our study was to describe the multiorgan manifestations of disseminated mucormycosis documented at CT and MRI in four patients and correlate these with the pathological findings and patient outcome. Irrespective of the site of infection, infarction or haemorrhage are the constant features of invasive mycosis. Identification of one or both of these two major imaging findings in immunocompromised patients should be regarded as an indicator of possible infection by angiotropic fungi, including the genre Mucorales.

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