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First published online June 22, 2006
British Journal of Radiology (2006) 79, 707-711
© 2006 British Institute of Radiology
doi: 10.1259/bjr/22522280

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Short communication

Quantitative optical coherence tomographic elastography: method for assessing arterial mechanical properties

J Rogowska, PhD1,2, N Patel, BS1, S Plummer, BS1 and M E Brezinski, MD, PhD1,2

1 Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, 2 Harvard Medical School, Boston, Massachusetts, USA

Correspondence: Mark E Brezinski, Brigham and Women's Hospital, MRB 106, 75 Francis Street, Boston, MA 02115, USA.

Optical coherence tomography elastography represents a potentially attractive new technique for measuring elastic properties of tissues on a micron scale. In this study, the feasibility of optical coherence tomography (OCT) to study the mechanical properties of phantoms and atherosclerotic arterial samples is reported. The elastic modulus of tissue-mimicking phantoms was measured using OCT and correlated with mechanical measurements. The results indicate that elastography based on OCT represents an attractive technique for evaluating the mechanical properties of tissues.







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