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British Journal of Radiology (2006) 79, 76-78
© 2006 British Institute of Radiology
doi: 10.1259/bjr/97645635

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Case report

Solitary pulmonary nodule with growth and contrast enhancement at CT: inflammatory pseudotumour as an unusual benign cause

S Diederich, Prof. Dr. med. 1 D Theegarten, Priv. Doz. Dr. med. 2 G Stamatis, Prof. Dr. med. 3 and R Lüthen, Priv. Doz. Dr. med. 4

1 Department of Diagnostic and Interventional Radiology, Marien Hospital, Academic Teaching Hospital, Rochusstr. 2, D-40479 Düsseldorf, 2 Institute of Pathology, BG-Kliniken Bergmannsheil, Ruhr University Bochum, 3 Department of Thoracic Surgery and Endoscopy, Ruhrland Hospital Essen and 4 Department of Medicine, Marien Hospital Düsseldorf, Germany

Small (≤10 mm) pulmonary nodules are frequently detected at modern chest CT. As most of these nodules are benign, non-invasive classification is required – usually based on assessment of growth and perfusion. Absence of growth and no evidence of perfusion, as demonstrated by lack of enhancement at contrast-enhanced CT or MRI, strongly suggest a benign nodule. On the other hand, growth with a doubling of the nodule's volume between 20 days and 400 days or enhancement suggest a malignant nature of the lesion. We present an example of a nodule with strong contrast enhancement and a doubling time of approximately 260 days, which histologically represented a benign inflammatory pseudotumour.







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