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British Journal of Radiology (2005) 78, 355-357
© 2005 British Institute of Radiology
doi: 10.1259/bjr/36150185
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Case report

The reverse target sign in liver disease: a potential ultrasound feature in cirrhotic liver nodules characterization

G J Kraus, MD1, P Schedlbauer, MD1, S Lax, MD2, D Zebedin, MD3 and F Flueckiger, MD1

Institutes of 1 Radiology and 2 Pathology, General Hospital Graz-West, Goestingerstrasse 22, 8020 Graz and 3 Department of Radiology, University Hospital Graz, Auenbruggerplatz 1, 8036 Graz, Austria

In patients with suspected liver disease, ultrasound is the most commonly performed initial imaging modality. We report a patient who had previously undiagnosed liver cirrhosis with target-shaped lesions interspersed throughout the liver parenchyma on ultrasound seen as multiple uniform round shaped lesions with varying isoechoic to hyperechoic centres surrounded by a hyperechoic rim. We have termed this the "reverse" target sign as there is inversion of the typical echoic pattern that is normally seen in metastatic liver disease. We suggest this ultrasound sign may represent a method for differentiating cirrhotic liver nodules from other nodular liver lesions.






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