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British Journal of Radiology (2003) 76, 566-569
© 2003 British Institute of Radiology
doi: 10.1259/bjr/29409091

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Case report

MRI diagnosis of bilateral adrenal vein thrombosis

M F Ryan, BSc, MB, FFR RCSI, FRCR 1 J P Murphy, FFR RCSI, FRCR, FRCPC 2 R Jay, MD, FRCPC 3 J Callum, MD, FRCPC 3 and D MacDonald, MD, FRCPC 4

1 Department of Clinical Radiology, Mayo General Hospital, Castlebar, Co. Mayo, Ireland, Departments of 2 Medical Imaging, 3 Medicine and 4 Clinical Pathology, Sunnybrook and Women's College Health Sciences Centre and the University of Toronto, Toronto, Ontario, Canada

Correspondence: Max F Ryan

We report a case of bilateral adrenal vein thrombosis in an adult female who had a history of breast cancer. The patient does not have clinical, serological or imaging evidence of metastatic disease 14 months from the initial diagnosis. Adrenal vein thrombosis is a rare entity. There have been no previous reports specifically stating an association between adrenal vein thrombosis and hypercoaguability, but there are many cases in the literature documenting venous thrombosis elsewhere within the body in patients with hypercoaguable states. Laboratory testing performed to exclude a hypercoaguable state, revealed heterozygosity for the Factor V Leiden mutation/activated protein C resistance and elevated factor VIII levels [3660 IU l-1 (<1500)]. This is the first reported case of bilateral metachronous adrenal vein thrombosis in which MRI established the diagnosis.







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