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British Journal of Radiology 75 (2002),843-846 © 2002 The British Institute of Radiology

Case report

Peripheral arterial insufficiency associated with protein C deficiency

Y P Cho, MD 1 D H Lee, MD 2 H J Jang, MD 1 J S Kim, MD 1 M S Han, MD 1 and S G Lee, MD 3

Departments of 1 General Surgery and 2 Diagnostic Radiology, Asan Kangnung Hospital, 415 Bangdong Ri, Sachun Myun, Kangnung and 3 Department of General Surgery, University of Ulsan Medical College and Asan Medical Center, 388-1 Poongnap Dong, Songpa Ku, Seoul, Republic of Korea

Two patients with protein C deficiency who presented with peripheral arterial insufficiency were successfully managed. One patient was managed with bypass surgery for focal gangrene followed by full anticoagulation whilst the other patient was managed with full anticoagulation. Both patients showed characteristic arteriographic findings. Patients who present with peripheral arterial insufficiency demonstrating thrombotic occlusion of main peripheral artery without atherosclerosis and other risk factors should be evaluated for hypercoagulable states.




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