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British Journal of Radiology 74 (2001),1065-1070 © 2001 The British Institute of Radiology

Pictorial review

Imaging appearances of metastases from neuroendocrine tumours of the pancreas

M P Debray, MD1, O Geoffroy, MD1, J P Laissy, MD, PhD1, R Lebtahi, MD2, O Silbermann-Hoffman1, M C Henry-Feugeas, MD, PhD1, G Cadiot, MD, PhD4, M Mignon, MD, PhD, FRCP(London)3 and E Schouman-Claeys, MD1

Departments of 1Radiology, 2Nuclear Medicine and 3Gastroenterology, Bichat-Claude-Bernard Hospital, 46 rue Henri Huchard, 75877 Paris Cedex 18 and 4Department of Gastroenterology, CHU de Reims, 51092 Reims Cedex, France

Endocrine tumours of the pancreas (ETPs) are rare neoplasms that are frequently malignant. Despite their usual slow growth, metastases do occur and have a major impact on prognosis. Metastases may be the first manifestation of disease, and recognition of particular radiological features of these hypervascular metastases should suggest their possible neuroendocrine origin. Although somatostatin receptor scintigraphy has changed the imaging strategy for these tumours and has become their principal imaging modality, radiological techniques are still required for precise localization of scintigraphic hot spots and monitoring of response to therapy. This pictorial review shows the typical radiological features of ETP metastases and emphasizes the role of different imaging modalities.




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