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British Journal of Radiology 74 (2001),1059-1061 © 2001 The British Institute of Radiology

Case report

Imaging of pulmonary manifestations in subtype B of Niemann–Pick disease

F Duchateau, MD, S Dechambre, MD and E Coche, MD

Department of Medical Imaging, Université Catholique de Louvain, Cliniques Universitaires Saint Luc, B-1200 Brussels, Belgium

Correspondence: E Coche, MD

We report the radiological and high resolution CT (HRCT) findings of the pulmonary involvement in a case of subtype B Niemann–Pick disease, diagnosed in an asymptomatic 22-year-old man, which was proved by bone marrow biopsy and sphingomyelinase assessment. In the present case, HRCT showed smooth interlobular septa thickening and a subtle ground-glass pattern.






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