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British Journal of Radiology (1996) 69, 914-919
© 1996 British Institute of Radiology
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The British Journal of Radiology, Vol 69, Issue 826 914-919, Copyright © 1996 by British Institute of Radiology

ARTICLES

The significance of low grade right iliac fossa uptake on 99Tcm-HMPAO labelled white cell scans

JH Small, EP Wraight, AH Freeman and KA Miles
Department of Radiology, Addenbrooke's Hospital NHS Trust, Cambridge, UK.

Technetium-99m HMPAO labelled white cell scanning is now an accepted method for assessing the activity of inflammatory bowel disease. However, false positive results have been demonstrated. This study was conducted to assess the significance of low grade uptake on 99Tcm-HMPAO labelled white cell scans in the right iliac fossa (RIF) in the context of possible inflammatory bowel disease (IBD). 32 patients over a period of 1 year had low grade RIF uptake as the predominant abnormality. 20 of these had no prior diagnosis of inflammatory bowel disease. Only one case in this group was subsequently diagnosed as having Crohn's disease. Nodular lymphoid hyperplasia (NLHP) and non-steroidal anti-inflammatory drugs (NSAIDs) were also associated with low grade RIF uptake. Possible explanations for these findings are discussed.


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K. Peacock, U. Porn, R. Howman-Giles, E. O'Loughlin, R. Uren, K. Gaskin, S. Dorney, and R. Kamath
99mTc-Stannous Colloid White Cell Scintigraphy in Childhood Inflammatory Bowel Disease
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[Abstract] [Full Text] [PDF]


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