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British Journal of Radiology (1996) 69, 567-569
© 1996 British Institute of Radiology
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The British Journal of Radiology, Vol 69, Issue 822 567-569, Copyright © 1996 by British Institute of Radiology

ARTICLES

Short communication: renal function and the excretion of contrast agents

P Dawson and AM Peters
Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

The renal excretion of intravascular iodinated X-ray and gadolinium chelate MR contrast is examined theoretically. An expression is derived for the proportion of an administered dose of such an agent excreted in any given time in the face of varying levels of renal function. It is shown that a family of curves may be generated from which an estimate of this proportion for any time may be made. Some circumstances in which such knowledge may be useful are briefly discussed.




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