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British Journal of Radiology (1996) 69, 266-268
© 1996 British Institute of Radiology
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The British Journal of Radiology, Vol 69, Issue 819 266-268, Copyright © 1996 by British Institute of Radiology


ARTICLES

Short communication: the use of sodium ironedetate (Sytron) as an MRI rectal contrast agent

PJ Buxton
Department of Radiology, Royal Naval Hospital Haslar, Gosport, UK.

The use of bowel contrast medium in abdominal and pelvic MRI examinations is increasingly being recognized as a useful adjunct. A contrast agent which produces a negative contrast effect with T2 weighted (T2W) sequences might help distinguish bowel pathology, which has increased signal intensity, from bowel content. A solution of 7.6 mg ml-1 of sodium ironedetate (Sytron, Link Pharmaceuticals) produces positive contrast on the first (proton density) echo and negative contrast (signal void) on the second (T2W) echo of a dual echo sequence at 0.5 T. When administered rectally it provides a negative contrast bowel marker for pelvic examinations.





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