The British Journal of Radiology, Vol 69, Issue 818 114-121, Copyright © 1996 by British Institute of Radiology

ARTICLES

Ganglioneuroma: computed tomography and magnetic resonance features

T Ichikawa, K Ohtomo, T Araki, H Fujimoto, K Nemoto, A Nanbu, M Onoue and K Aoki
Department of Radiology, Yamanashi Medical College, Japan.

12 patients who had histological proven ganglioneuromas were investigated by computed tomography (CT) and magnetic resonance (MR) imaging. CT scans (n = 11), conventional spin-echo MR images (n = 10) and dynamic MR images (n = 5) were acquired. All lesions showed a well defined, oval shape. Five lesions (42%) showed calcification which was punctate in four and coarse in one on CT. CT attenuation was predominantly low in three of 10 (30%) and intermediate in the remaining seven (70%). In all lesions MR signals were mainly of low intensity on T1 weighted images (T1WI) and of high intensity on T2 weighted images (T2WI). Dynamic MR studies in five cases showed a lack of early enhancement but gradual increasing enhancement. One case had a ganglioneuroblastoma component which showed soft-tissue density and coarse calcifications on CT scans, MR images with intermediate intensity on T1WI and T2WI and early enhancement and little washout on dynamic MR images. In conclusion, ganglioneuroma typically shows punctate calcification and low attenuation on CT and marked hyperintensity on T2WI with gradual increasing enhancement on dynamic MR images. If a ganglioneuroma has atypical CT and MR features, coexistence of a malignant component should be considered.

This article has been cited by other articles:

				P. Bougneres, L. Pantalone, A. Linglart, A. Rothenbuhler, and C. Le Stunff Endocrine Manifestations of the Rapid-Onset Obesity with Hypoventilation, Hypothalamic, Autonomic Dysregulation, and Neural Tumor Syndrome in Childhood J. Clin. Endocrinol. Metab., October 1, 2008; 93(10): 3971 - 3980. [Abstract] [Full Text] [PDF]

				S. Duffy, M. Jhaveri, J. Scudierre, E. Cochran, and M. Huckman MR Imaging of a Posterior Mediastinal Ganglioneuroma: Fat as a Useful Diagnostic Sign AJNR Am. J. Neuroradiol., November 1, 2005; 26(10): 2658 - 2662. [Abstract] [Full Text] [PDF]

				S. E. Rha, J. Y. Byun, S. E. Jung, H. J. Chun, H. G. Lee, and J. M. Lee Neurogenic Tumors in the Abdomen: Tumor Types and Imaging Characteristics RadioGraphics, January 1, 2003; 23(1): 29 - 43. [Abstract] [Full Text] [PDF]

				G. J. Lonergan, C. M. Schwab, E. S. Suarez, and C. L. Carlson From the Archives of the AFIP : Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma: Radiologic-Pathologic Correlation RadioGraphics, July 1, 2002; 22(4): 911 - 934. [Abstract] [Full Text] [PDF]

				H. Nishimura, Y. Zhang, K. Ohkuma, M. Uchida, N. Hayabuchi, and S. Sun MR Imaging of Soft-Tissue Masses of the Extraperitoneal Spaces RadioGraphics, September 1, 2001; 21(5): 1141 - 1154. [Abstract] [Full Text] [PDF]

				K. MITHÖFER, E. F. GRABOWSKI, A. E. ROSENBERG, D. P. RYAN, and H. J. MANKIN Symptomatic Ganglioneuroma of Bone. A Case Report J. Bone Joint Surg. Am., November 1, 1999; 81(11): 1589 - 95. [Full Text]

				P. Otal, G. Escourrou, C. Mazerolles, B. J. D'Othee, S. Mezghani, S. Musso, D. Colombier, H. Rousseau, and F. Joffre Imaging Features of Uncommon Adrenal Masses with Histopathologic Correlation RadioGraphics, May 1, 1999; 19(3): 569 - 581. [Abstract] [Full Text] [PDF]