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The British Journal of Radiology, Vol 68, Issue 814 1123-1125, Copyright © 1995 by British Institute of Radiology
ARTICLES |
ME Stein, K Drumea, JN Guilbord, O Ben-Itzhak and A Kuten
Department of Oncology, Rambam Medical Center, Haifa, Israel.
The clinical, radiological and pathological findings in a 28-year-old female patient who developed aggressive meningioma 20 years after prophylatic cranial irradiation (PCI) for acute lymphoblastic leukaemia (ALL) are described here. Only four cases of late atypical/aggressive meningioma following PCI were detected in a thorough search of the literature. The high cure rate in childhood ALL, attributable to aggressive chemotherapy and PCI, is capable of inducing secondary brain tumour, including aggressive meningioma.
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