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Radiation and Cancer Biology Non-topic Meeting 25 February 1994

It has been suggested by Denekamp [1] that an agent with selective toxicity towards the vasculature of solid tumours would present an effective means of therapy, as many thousands of tumour cells are dependent on each blood vessel for survival. Evidence supporting the underlying theory has come from the study of novel agents and therapies as well as conventional chemotherapeutics which demonstrate important antivascular components to their tumouricidal activities.