This Article Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Cornford, E J Articles by Blamey, R W Search for Related Content PubMed PubMed Citation Articles by Cornford, E J Articles by Blamey, R W

Mammographic features of invasive lobular and invasive ductal carcinoma of the breast: a comparative analysis

¹ Department of Radiology, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK ² Department of Surgery, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK ³ Department of Pathology, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK

The mammographic appearances of 86 invasive lobular carcinomas were compared with those of 86 invasive ductal carcinomas of no special type matched for age, size and stage. There was no significant difference in the frequency of a mammographic abnormality consistent with malignancy between the lobular carcinoma (90%) and ductal carcinoma (96%) groups. A spiculate mass was the commonest feature in both groups (69% and 63%, respectively). There were no differences in the imaging features of masses in the two groups. In the lobular carcinoma group any mammographic abnormality was more likely to be seen on only one view and calcifications were less frequently observed. Multiple lesions were more frequent in the ductal carcinoma group. However, although these differences appeared to reach statistical significance, as they were only apparent in a study with a large number of comparisons, it is unlikely that these differences are practically significant. Analysis of the lobular invasive group failed to demonstrate any significant differences in the imaging features of the classical and mixed sub-types, a spiculate mass being the most common single abnormality in both. No mammographic differences of practical use to distinguish invasive lobular from invasive ductal carcinoma of no special type were demonstrated.

Received for publication September 30, 1994. Revision received December 16, 1994. Accepted for publication December 21, 1994.

This article has been cited by other articles:

				S. Doyle, A. J. Evans, E. A. Rakha, A. R. Green, and I. O. Ellis Influence of E-cadherin Expression on the Mammographic Appearance of Invasive Nonlobular Breast Carcinoma Detected at Screening Radiology, October 1, 2009; 253(1): 51 - 55. [Abstract] [Full Text] [PDF]

				S GARNETT, M WALLIS, and G MORGAN Do screen-detected lobular and ductal carcinoma present with different mammographic features? Br. J. Radiol., January 1, 2009; 82(973): 20 - 27. [Abstract] [Full Text] [PDF]

				N. Biglia, L. Mariani, L. Sgro, P. Mininanni, G. Moggio, and P. Sismondi Increased incidence of lobular breast cancer in women treated with hormone replacement therapy: implications for diagnosis, surgical and medical treatment Endocr. Relat. Cancer, September 1, 2007; 14(3): 549 - 567. [Abstract] [Full Text] [PDF]

				W. P. Evans, L. J. Warren Burhenne, L. Laurie, K. F. O'Shaughnessy, and R. A. Castellino Invasive Lobular Carcinoma of the Breast: Mammographic Characteristics and Computer-aided Detection Radiology, October 1, 2002; 225(1): 182 - 189. [Abstract] [Full Text] [PDF]

				A. Qayyum, R. L. Birdwell, B. L. Daniel, K. W. Nowels, S. S. Jeffrey, T. A. Agoston, and R. J. Herfkens MR Imaging Features of Infiltrating Lobular Carcinoma of the Breast: Histopathologic Correlation Am. J. Roentgenol., May 1, 2002; 178(5): 1227 - 1232. [Abstract] [Full Text] [PDF]