This Article Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Reinecke, L Articles by Thornley, A L Search for Related Content PubMed PubMed Citation Articles by Reinecke, L Articles by Thornley, A L

Radiotherapy—an effective treatment for vaginal verrucous carcinoma

¹ Witwatersrand University and Garden City Clinic, Johannesburg, South Africa ² Department of Zoology, Witwatersrand University, PO Wits 2050 Johannesburg, South Africa

Vaginal carcinoma makes up 1%–2% of all gynaecological tumours. Verrucous carcinoma of the vagina is even more rare—only 16 cases are reported in the scientific literature. A case of a complete regression after 60 Gy fractionated radiotherapy by a tumour 12 cm³ in size is reported. Most authors are of the opinion that radiotherapy causes anaplastic transformation of verrucous carcinoma. The minority view, that anaplastic transformation does not occur, is correct and is supported by our clinical and radiological data. The conflicting literature on vaginal verrucous carcinoma (VVC) is reviewed with reference to verrucous carcinoma at other sites.

Received for publication June 24, 1992. Revision received September 1, 1992. Accepted for publication September 28, 1992.