This Article Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Laskey, M. A. Articles by Compston, J. E. Search for Related Content PubMed PubMed Citation Articles by Laskey, M. A. Articles by Compston, J. E.

Comparison of the effect of different reference data on Lunar DPX and Hologic QDR-1000 dual-energy X-ray absorptiometers

M. A. Laskey, DPhil A. J. Crisp, FRCP ^* T. J. Cole, PhD and J. E. Compston, FRCP

Bone Density Unit, Department of Nuclear Medicine, Cambridge CB2 2QQ ^* Department of Rheumatology, Addenbrooke's Hospital, Cambridge CB2 2QQ Department of Medicine, University of Cambridge Clinical School, Addenbrooke's Hospital, Cambridge CB2 2QQ MRC Dunn Nutritional Laboratory, Downhams Lane, Milton Road, Cambridge CB4 1XJ, UK

We have investigated whether the Lunar DPX (software 3.4) and Hologic QDR-1000 dual-energy X-ray absorptiometers have comparable normal reference databases for the spine and femur of white UK and USA subjects. After conversion for systematic differences in absolute bone density values between the two systems, the reference databases were very similar for the spine in young subjects, but there were clear differences in the femur databases of young females and males of all ages. These differences were confirmed by comparing the percent age-matched and young values determined by the two systems for subjects scanned on both systems. Thus the diagnosis and management of a patient could differ, depending on the system used for the bone density measurements.

Key Words: Dual-energy X-ray absorptiometry • Reference data • Lunar DPX • Hologic QDR-1000

Received for publication May 8, 1992. Revision received June 25, 1992. Accepted for publication July 13, 1992.

This article has been cited by other articles:

				C Christodoulou and C Cooper What is osteoporosis? Postgrad. Med. J., March 1, 2003; 79(929): 133 - 138. [Abstract] [Full Text] [PDF]

				H. D. Nelson, M. Helfand, S. H. Woolf, and J. D. Allan Screening for Postmenopausal Osteoporosis: A Review of the Evidence for the U.S. Preventive Services Task Force Ann Intern Med, September 17, 2002; 137(6): 529 - 541. [Abstract] [Full Text] [PDF]

				A. Simmons, S. Barrington, M. J O'Doherty, and A. J Coakley Bone mineral densitometry in clinical practice BMJ, November 11, 1995; 311(7015): 1300b - 1301. [Full Text]

				J. Compston, C. Cooper, and J. Kanis Authors' reply BMJ, November 11, 1995; 311(7015): 1301a - 1301. [Full Text]

				J E Compston, C Cooper, and J A Kanis Fortnightly Review: Bone densitometry in clinical practice BMJ, June 10, 1995; 310(6993): 1507 - 1510. [Abstract] [Full Text]