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Transitional cell carcinoma of the bladder associated with Crohn's disease: case report and review of the literature

Y. Fujimura, MD ^* T. Kihara, MD J. Uchida, MD K. Hoshika, MD I. Sato, MD ^* T. Eimoto, MD Y. Furukawa, MD A. Sone, MD and K. Ohashi, MD

^* Divisions of Gastroenterology, Department of Internal Medicine Divisions of Nephrology, Department of Internal Medicine Department of Urology, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701–01, Japan Department of Family Practice, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701–01, Japan

This excerpt was created in the absence of an abstract.

Transitional cell carcinoma of the bladder rarely occurs within the first two decades of life. We report a case of transitional cell cancer of the bladder complicating Crohn's disease and review the relevant literature.

The patient was a 15-year-old boy admitted to hospital in May 1990 with a fever and diarrhoea of four years' duration. There was no relevant past or family history. On admission, his temperature was 38.2°C and there was tenderness on palpation of the right lower quadrant. Laboratory findings on admission were as follows: white blood cell count was normal, C-reactive protein was 4.2 mg/dl (normal < 0.3 mg/dl), the erythrocyte sedimentation rate was 30 mm/h, albumin was 2.2 g/dl (normal, 3.5–4.5 g/dl), cholesterol was 92 mg/dl (normal, 130–220 mg/dl) and other blood tests were within normal limits. There were 20–25 red blood cells per high-power field in his urine. A chest radiograph was normal.

Key Words: Transitional cell carcinoma • Bladder tumour • Crohn's disease • Adolescent

Received for publication November 25, 1991. Revision received March 12, 1992. Accepted for publication March 26, 1992.