This Article Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Cowan, N. C. Articles by Moxham, J. Search for Related Content PubMed PubMed Citation Articles by Cowan, N. C. Articles by Moxham, J.

Intrathoracic lymphadenopathy and HIV infection

N. C. Cowan, MA, MB, BChir, FRCR J. R. Salisbury, BSc, MB, BS, MRCPath ^* and J. Moxham, MD, FRCP

Department of Radiology, King's College Hospital, London SE5 9RS, UK ^* Department of Pathology, King's College Hospital, London SE5 9RS, UK Department of Thoracic Medicine, King's College School of Medicine and Dentistry, Bessemer Road, London SE5 9PJ, UK

This excerpt was created in the absence of an abstract.

A 32-year-old homosexual man, known to be HIV-seropositive for 7 years, presented with a 2-month history of a productive cough, night sweats, lethargy, right-sided upper chest discomfort and exertional dyspnoea. He smoked 10–20 cigarettes per day. There was no other relevant past medical history.

The patient looked thin and unwell but was afebrile. Small lymph nodes were palpable in the neck, axillae and groin. A chest radiograph showed right paratracheal lymphadenopathy with adjacent ill-defined air-space consolidation in the right upper lobe (Fig. 1). At fibreoptic bronchoscopy the only abnormality was tracheal indentation from the right. Other investigations at presentation included a blood CD4 lymphocyte count of 386/mm³ (normal value > 1000/mm³,) a CD8 lymphocyte count of 1819/mm³, Hb 13.6 g/dl, WBC 10.6 x 10⁹, granulocytes 7.7 x 10⁹/l, lymphocytes 2.7 x 10⁹/1; urea, electrolytes and liver function tests were normal except for an elevated alkaline phosphatase (105 IU/1).

Key Words: Human immunodeficiency virus (HIV) infection • Intrathoracic lymphadenopathy • Bronchogenic carcinoma • Computed tomography

Received for publication December 16, 1991. Revision received April 6, 1992. Accepted for publication April 30, 1992.