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Efficacy of low-dose iodine-131 ablation of post-operative thyroid remnants: a study of 69 cases

Department of Clinical Oncology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong

Low-dose iodine-131 of mean activity 1117 MBq was used to ablate post-operative thyroid remnants in 69 patients with differentiated thyroid cancer. Successful ablation was defined as uptake of less than 1% at 48 h and absence of visible image on the post-ablation scan. Ablation by one dose was successful in 95% of patients after total or subtotal thyroidectomy, and 56% of patients after partial or hemithyroidectomy. All patients with uptake of 10% or less on the pre-ablation scan had successful ablation. The results are compared with other reports using low-dose radioiodine ablation and the significance of the findings discussed.

Key Words: Thyroid cancer • Radioiodine

Received for publication December 16, 1991. Revision received April 14, 1992. Accepted for publication May 8, 1992.

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