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British Journal of Radiology (1992) 65, 857-860
© 1992 British Institute of Radiology
doi: 10.1259/0007-1285-65-778-857

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Doppler ultrasound scanning in the detection of renal artery stenosis in hypertensive patients

Cornelis T. Postma, MD Joost van Aalen, MD Theo de Boo, MSc * Gerd Rosenbusch, MD, PhD {dagger} and Theo Thien, MD, PhD

Department of Medicine, Division of General Internal Medicine, University Hospital, Postbox 9101, 6500 HB Nijmegen, The Netherlands * Department of Medical Satistics, University Hospital, Postbox 9101, 6500 HB Nijmegen, The Netherlands {dagger} Department of Diagnostic Radiology, University Hospital, Postbox 9101, 6500 HB Nijmegen, The Netherlands

The diagnostic accuracy of Doppler ultrasound in the detection of renal arterial disease has been assessed in a prospective study of 61 hypertensive patients. The findings of Doppler ultrasound were compared with the results of renal angiography. In 15 patients (24.5%) no accurate Doppler signs could be obtained and the Doppler ultrasound examination was considered a technical failure. Of the remaining 46 patients, 24 had renal artery stenosis. Nine of the stenoses were not detected by Doppler ultrasound and in three patients a false positive diagnosis of renal artery stenosis was made. The sensitivity of Doppler ultrasound was 62.5%, the specificity 86.4% and the overall diagnostic acccuracy was 73.9%. By comparing the 15 patients in whom Doppler ultrasound failed with the 46 in whom it was successful, age appeared to be higher and creatinine clearance lower in the failure group. By comparing the 34 patients with true positive and true negative results with the 12 patients with false results, no significant differences were found. In a multivariate analysis, higher age showed a significant relation to failure of Doppler ultrasound. Doppler ultrasound has limited value in the screening of hypertensive patients for renal artery stenosis.

Key Words: Doppler ultrasound scanning • Renal artery stenosis • Hypertension

Received for publication November 4, 1991. Revision received April 6, 1992. Accepted for publication April 28, 1992.




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