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Contrast extravasation from a Pulse-Tec graft: a complication of high-dose recombinant tissue-type plasminogen activator therapy

Department of Radiology, St George's Hospital, Blackshaw Road, London SW17 OQT, UK ^* Department Surgery, St George's Hospital, Blackshaw Road, London SW17 OQT, UK

This excerpt was created in the absence of an abstract.

Transmural contrast extravasation through both knitted Dacron and Gore-Tex grafts is well documented. Reports have appeared associating this complication with the use of both streptokinase and urokinase (Rabe et al, 1982; Becker et al, 1984; Rosner & Doris, 1984; Perler et al, 1986). We report a case of extravasation through a Pulse-Tec (Newtec Vascular Products Ltd, UK) graft in association with the use of high-dose recombinant tissue plasminogen activator (rt-PA) therapy. This complication has not previously been reported in this type of graft or with this particular thrombolytic agent.

Key Words: Thrombolysis • Extravasation • Recombinant tissue plasminogen activator (rt-PA) • Pulse-Tec

Received for publication August 1, 1991. Revision received October 17, 1991. Accepted for publication November 20, 1991.