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Duplex Doppler ultrasound in the investigation of occult nephropathy following haemolytic uraemic syndrome

Department of Radiology, Institute of Child Health and the Hospital for Sick Children, Great Ormond Street, London, UK ^* Department of Paediatric Nephrology, Institute of Child Health and the Hospital for Sick Children, Great Ormond Street, London, UK

Duplex doppler ultrasound has been reported to be of value in the detection of raised vascular resistance, particularly in the renal tract. A prospective single blind study investigating the use of duplex Doppler ultrasound to measure resistive index (RI) in patients with impaired renal function and a history of diarrhoea-associated haemolytic uraemic syndrome (D+ HUS) was performed. There was considerable overlap in the range of RIs, with RIs greater than 70% in children with normal renal function and in those with renal impairment following D+ HUS. There was no significant difference in the mean RI between the groups studied. We feel that the RI is not of value in predicting the presence of occult nephropathy following haemolytic uraemic syndrome.

Key Words: Doppler • Nephropathy • Haemolytic uraemic syndrome

Received for publication May 13, 1991. Revision received August 5, 1991. Accepted for publication September 20, 1991.