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British Journal of Radiology (1992) 65, 75-78
© 1992 British Institute of Radiology
doi: 10.1259/0007-1285-65-769-75

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Malignant paraganglioma of the mediastinum: a further diagnostic and therapeutic use of radiolabelled mIBG

E. J. Cornford, MRCP M. L. Wastie, MRCP, FRCR and D. A. L. Morgan, FRCR *

University Hospital, Radiology Department, Queen's Medical Centre, Nottingham NG7 2UH * Department of Clinical Oncology, General Hospital, Park Row, Nottingham, UK

This excerpt was created in the absence of an abstract.

The paraganglia are widely dispersed collections of specialized neural crest cells arising in association with the segmental or collateral autonomic ganglia (Enzinger & Weiss, 1988). The extra-adrenal paraganglia can be best classified by their anatomical site (Glenner & Grimley, 1974).

(1) Branchiomeric paraganglia arise in association with the arteries and cranial nerves of the head and neck. Carotid body and glomus jugulare tumours are neoplasms arising from these paraganglia.

(2) Intravagal paraganglia are located within the perineurium of the vagus nerve and a vagus body tumour is an example of this type.

(3) Aorticosympathetic paraganglia arise in association with the sympathetic nervous system. Aortic body tumours and retroperitoneal paragangliomas are examples of tumours from these paraganglia.

Key Words: Paraganglioma • mIBG

Received for publication March 15, 1991. Revision received June 20, 1991. Accepted for publication July 2, 1991.







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