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Malignant fibrous histiocytoma: an unusual presentation

Department of Diagnostic Radiology, Christie Hospital and Holt Radium Institute, Wilmslow Road, Withington, Manchester M20 9BX, UK ^* Hope Hospital, Eccles Old Road, Salford, UK

Correspondence: Author for correspondence: Dr P. M. Hughes, Department of Diagnostic Radiology, Christie Hospital and Holt Radium Institute.

This excerpt was created in the absence of an abstract.

Malignant fibrous histiocytoma (MFH) is the commonest type of adult soft tissue sarcoma (Weiss & Enzinger, 1978). Intracranial MFHs, however, are rare and unreported in children. We report a case of MFH presenting as a posterior fossa mass in a 9-year-old boy with homocystinuria (HCU). This is an unusual presentation and the computed tomography (CT) finding of localized skull vault destruction proved an important differentiating feature from primary posterior fossa tumours. Early diagnosis of MFH is important as primary wide excision of involved bone margins improves prognosis, irrespective of subsequent radiotherapy or adjuvant chemotherapy (Tracy et al, 1984).

Key Words: Malignant fibrous histiocytoma • Intercranial • Computed tomography

Received for publication November 1, 1990. Revision received December 1, 1990.