This Article Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by O'Connell, M. E. A. Articles by Harmer, C. L. Search for Related Content PubMed PubMed Citation Articles by O'Connell, M. E. A. Articles by Harmer, C. L.

Malignant struma ovarii: presentation and management

Gynaecology and Thyroid Units, The Royal Marsden Hospital, Fulham Road, London SW3 6JJ

This excerpt was created in the absence of an abstract.

Struma ovarii are rare tumours and just over 400 cases are reported in the world literature (Gould et al, 1983). The incidence of malignancy is reported as 5–10% of all cases of struma ovarii (Marcus & Marcus, 1961) but has been reported as less (Gould et al, 1983). The metastasis rate is estimated to be 5–6% (Emge, 1940) and only 21 cases with metastases have so far been reported (Dalley, 1970; Pardo-Mindan & Vazquez, 1983; Willemse et al, 1987; Rosenblum et al, 1989). Owing to their rarity, there is no universal agreement as to management. Surgical excision continues to remain the initial definitive primary treatment. However, metastatic and recurrent malignant struma ovarii have been treated with radioactive ¹³¹I (Woodruff et al, 1966; Kempers et al, 1970; Willemse et al, 1987). Intra-peritoneal radiocolloids (Woodruff et al, 1966; Rosenblum et al, 1989) and external beam radiotherapy (Gonzalez-Angulo et al, 1963; Woodruff et al, 1966; Pardo-Mindan & Vazquez, 1983) have also found a useful role in palliation.

This paper describes the presentation and management of two patients with malignant struma ovarii referred to the Royal Marsden Hospital between 1945 and 1989, during which time nearly 3000 other ovarian tumours were recorded.

A 35-year-old married woman with no previous or family history of thyroid disease presented in 1951 with severe recurrent abdominal pain. Laparotomy was performed and both ovaries were found to be cystic.

Received for publication July 1, 1989. Revision received September 1, 1989.

This article has been cited by other articles:

				M. D. Navarro, M. A. L. Tan, J. L. Lovecchio, and S. I. Hajdu Malignant Struma Ovarii Ann. Clin. Lab. Sci., January 1, 2004; 34(1): 107 - 112. [Abstract] [Full Text] [PDF]

				P. Rotman-Pikielny, J. C. Reynolds, W. C. Barker, P. M. Yen, M. C. Skarulis, and N. J. Sarlis Recombinant Human Thyrotropin for the Diagnosis and Treatment of a Highly Functional Metastatic Struma Ovarii J. Clin. Endocrinol. Metab., January 1, 2000; 85(1): 237 - 244. [Abstract] [Full Text]

				A Bhansali, V Jain, A Rajwanshi, S Lodha, and R J Dash Follicular carcinoma in a functioning struma ovarii Postgrad. Med. J., October 1, 1999; 75(888): 617 - 618. [Abstract] [Full Text]