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British Journal of Radiology (1989) 62, 1056-1058
© 1989 British Institute of Radiology
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The British Journal of Radiology, Vol 62, Issue 744 1056-1058, Copyright © 1989 by British Institute of Radiology

ARTICLES

The influence of buscopan on adverse reactions to intravascular contrast media

S Sharma, M Rajani, A Khosla, N Misra and RK Goulatia
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi.

We have analysed the ability of prior intravenous Buscopan (hyoscine butylbromide) injection to influence the incidence and severity of adverse reactions to intravascularly administered, iodinated, ionic contrast medium in 258 consecutive digital subtraction angiographic (DSA) examinations. Adverse reactions were seen in 7.9% of the intravenous and 2.4% of the intra-arterial DSA examinations. The incidence of adverse reactions with and without prior Buscopan injection during intravenous DSA examinations was 8.2% and 7.1%, respectively and during intra-arterial DSA examinations was 5.6% and 1.5%, respectively. This difference is not statistically significant (chi 2-test). We conclude that prior intravenous injection of Buscopan has no influence on the incidence or severity of adverse reactions to intravascular contrast media.


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