This Article Full Text (PDF) Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Fowler, J. F. Search for Related Content PubMed Articles by Fowler, J. F.

The linear-quadratic model

Gray Laboratory of the Cancer Research Campaign, Mount Vernon Hospital, Northwood, Middlesex HA6 2RN

This excerpt was created in the absence of an abstract.

In Scott's (1987) letter in the October issue of BJR he asked "Is a tumour an early-responding tissue?" and emphasized the difficulties of deriving /β ratios for tumours. He questioned the clinical implications of the findings of Williams et al (1985), who reviewed the literature and found relatively high values of /β, resembling those of early reacting tissues. Williams et al had only considered experiments where reoxygenation was minimized by the use of clamping, hyperbaric oxygen or misonidazole, and they were aware that proliferation in the tumour could lead to decreased values of /β.

Received for publication January 1, 1988.