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Departments of Radiology, University Hospital Dijkzigt, Rotterdam, The Netherlands * Pathology, University Hospital Dijkzigt, Rotterdam, The Netherlands
The toxic effects of Hytrast were studied on the peritoneum of laboratory rats in order to define the lethal dose and possible causes of toxicity. The results show that Hytrast, due to its toxicity, should not be used in any clinical situation where gastrointestinal tract perforation or leakage is a possibility.
Present address: Laboratory of Experimental Surgery, Antoni van Leeuwenhoek Ziekenhuis, Cancer Institute of the Netherlands, Amsterdam, The Netherlands.
Received for publication April 1, 1986.
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