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British Journal of Radiology (1986) 59, 379-383
© 1986 British Institute of Radiology
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The British Journal of Radiology, Vol 59, Issue 700 379-383, Copyright © 1986 by British Institute of Radiology

ARTICLES

The results of a randomised trial of mixed-schedule (neutron/photon) irradiation in the treatment of supratentorial Grade III and Grade IV astrocytoma

W Duncan, J McLelland, WJ Jack, SJ Arnott, P Davey, A Gordon, GR Kerr and JR Williams

A randomised trial is reported of mixed-schedule (neutron/photon) irradiation compared with photon therapy for patients with Grade III or Grade IV astrocytoma. Thirty-one patients were allocated to be treated by the neutron/photon regime and 30 patients by photons. The median survival was 4 months in the mixed-schedule group and 8 months in the photon group. The survival rates were not significantly different. All patients who died had evidence of residual brain tumour. None had signs of radiation-related morbidity.




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