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British Journal of Radiology (1986) 59, 355-357
© 1986 British Institute of Radiology
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The British Journal of Radiology, Vol 59, Issue 700 355-357, Copyright © 1986 by British Institute of Radiology

ARTICLES

Correlation of human NMR T1 values measured in vivo and brain water content

HL MacDonald, BA Bell, MA Smith, DM Kean, JL Tocher, RH Douglas, JD Miller and JJ Best

A relationship has been demonstrated between nuclear magnetic resonance (NMR) longitudinal relaxation times (T1 values) obtained in vivo in both normal and oedematous (peritumoral) brain tissue, and measurements of brain water obtained by gravimetric analysis of operative samples. Significant correlations were found in seven patients in both cortex (r = 0.97, P less than 0.001) and white matter (r = 0.92, P less than 0.001). These findings suggest that NMR may prove a useful technique for monitoring brain oedema.


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