This Article Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Trigaux, J. P. Articles by Fays, F. d. Search for Related Content PubMed PubMed Citation Articles by Trigaux, J. P. Articles by Fays, F. d.

Comparative study of two iodinated contrast media containing 20% iodine in lower-limb phlebography: ioxaglate versus a conventional product

J. P. Trigaux, M.D. ^* R. de Fays, M.D. and F. de Fays, M.D. ^*

^* Service de Radiologie (Prof. P. Bodart), Cliniques UCL de Mont-Godinne, B-5180 Yvoir, Belgium Service de Radiologie, Clinique Saint-Joseph, B-6700 Arlon, Belgium

Forty-eight patients were examined by bilateral ascending phlebography in a crossover, prospective, randomised, doubleblind study. A low-osmolar agent (Hexabrix) (ioxaglate, 200 mg iodine/ml) and a dilute conventional contrast medium (Angiografin) (meglumine diatrizoate) with the same iodine concentration were used for each limb alternately.

The adverse reactions and the quality of diagnostic data were recorded: the Student paired-t-test showed statistically that ioxaglate containing 200 mg iodine per ml was better tolerated and that diagnostic information was equally good for the deep and ilio-caval systems, but seemed better with diatrizoate for superficial veins with extensive varicosity.

The authors conclude that ioxaglate 200 is advantageous overall in lower-limb phlebography from the standpoints of tolerance, diagnostic data and cost.

Received for publication July 1, 1984.