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British Journal of Radiology (1981) 54, 768-772
© 1981 British Institute of Radiology
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The British Journal of Radiology, Vol 54, Issue 645 768-772, Copyright © 1981 by British Institute of Radiology

ARTICLES

A study of the effect of sodium/meglumine ioxaglate (Hexabrix) on thyroid function

RG Grainger and GW Pennington

The effect of thyroid function was investigated in 22 patients undergoing arteriography with a new low osmolality contrast medium--sodium and meglumine ioxaglate (Hexabrix). Plasma thyroxine (T4), thyroxine resin uptake (TRU) and free thyroxine index (FTI) were measured before and at varying intervals up to 56 days after the arteriogram. Despite the large doses of Hexabrix used (up to 89.6 g of iodine), these tests of thyroid function did not reveal any significant change from pre-angiographic levels. It is concluded that Hexabrix as used for arteriography does not affect thyroid function.




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