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British Journal of Radiology (1981) 54, 592-596
© 1981 British Institute of Radiology
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The British Journal of Radiology, Vol 54, Issue 643 592-596, Copyright © 1981 by British Institute of Radiology

ARTICLES

Effects of acute administration of ethane hydroxydiphosphonate (EHDP) on skeletal scintigraphy with technetium-99m methylene diphosphonic acid (Tc-MDP) in the rat

I Watt and P Hill

A study has been performed in the rat to assess the effect of EHDP on the distribution of 99Tcm-labelled MDP used for skeletal imaging. Profound alterations in bone, kidney and blood levels were observed. These observations cast doubt on the value of bone scans for monitoring the therapeutic effect of diphosphonates.


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J. A. Carrasquillo, M. Whatley, V. Dyer, W. D. Figg, and W. Dahut
Alendronate Does Not Interfere with 99mTc-Methylene Diphosphonate Bone Scanning
J. Nucl. Med., September 1, 2001; 42(9): 1359 - 1363.
[Abstract] [Full Text] [PDF]


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