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British Journal of Radiology (1981) 54, 29-35
© 1981 British Institute of Radiology
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The British Journal of Radiology, Vol 54, Issue 637 29-35, Copyright © 1981 by British Institute of Radiology

ARTICLES

Radiation myelopathy in patients treated for carcinoma of bronchus using a six fraction regime of radiotherapy

S Dische, WM Martin and P Anderson

The adoption of a six-fraction regime of radiotherapy for patients with locally advanced carcinoma of the bronchus was followed by the appearance of radiation myelitis in eight cases. These were among a group of 130 patients given radiotherapy with anterior and posterior treatment fields, without shielding of the spinal cord. Radiation myelitis was found only in those where the calculated spinal-cord dose exceeded 3350 cGy (rad). The possible precipitating factors in the eight patients who suffered myelopathy were compared with those in the remaining 62 patients who also received spinal-cord doses calculated to be greater than 3350 cGy (rad). Only one difference was found--the haemoglobin concentration was significantly higher in those who suffered neuropathy compared with those who did not (P = 0.05).




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