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Lymphograms in prostatic carcinoma: false-positive and false-negative assessments in radiology

Institute of Urology and St. Peter's Hospitals, London

Forty patients with prostatic carcinoma underwent lymphography and pelvic lymphadenectomy. Node-by-node comparisons between radiology and histology findings yielded high false-negative rates for the lymphogram as a staging tool. False-positive and false-negative rates depend on the viewpoint taken: we argue that these rates should be expressed in terms of the disease, not the in vivo test. Lymphography has serious defects as a staging manoeuvre, but pelvic lymphadenectomy carries greater morbidity and mortality in its train.

^* Present address: Department of Radiology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ.

Received for publication June 1, 1980.