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Chronic oesophageal stricture due to moniliasis

Departments of Radiology and Medicine, Duke University Medical Center, Durham, North Carolina, 27710, U.S.A

This excerpt was created in the absence of an abstract.

Treatment of oesophageal moniliasis with nystatin and amphotericin B usually results in rapid recovery. A case is presented in which, despite complete relief of symptoms after anti-monilial therapy, a permanent stricture developed necessitating placement of a feeding gastrostomy. Athey et al. (1977) observed one stricture in 17 patients with oesophageal moniliasis confirmed by culture, suggesting this to be a rare complication.

A 17-year-old male was found to have acute myelogenous leukaemia. Haematological evaluation revealed a haemoglobin of 7.9 g%, a platelet count of 45 000/mm³ and a white blood cell count of 9400/mm³ with 90% blast cells. A bone marrow aspirate yielded 90% immature myeloid blast cells.

He was treated with two courses of cytosine arabinoside and daunorubicin hydrochloride. During the first course he developed fever and dysphagia. A double contrast barium swallow showed evidence of monilial oesophagitis (Fig. 1). Monilia was cultured from the oropharynx.

^* Picker Scholar, James Picker Foundation.

Received for publication March 1, 1978.