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A linear transform of the multi-target survival curve

University and MRC departments of Clinical Oncology and Radiotherapeutics, The Medical School, Hills Road, Cambridge, CB2 2QH

This excerpt was created in the absence of an abstract.

A completely linear transform of the multi-target survival curve is presented. This enables all data, including those on the shoulder region of the curve, to be analysed. The necessity to make a subjective assessment about which data points to exclude for conventional methods of analysis is, therefore, removed. The analysis has also been adapted to include a "Pike-Alper" method of assessing dose modification factors. For the data cited this predicts compatibility with the hypothesis of a true oxygen "dose-modification" whereas the conventional Pike-Alper analysis does not.

Received for publication November 1, 1977. Revision received February 1, 1978.